Certain medications may contribute to easy bruising by decreasing the blood's ability to clot. These include aspirin; ibuprofen (Advil, Motrin IB, others); naproxen sodium (Aleve); anticoagulant medications, such as warfarin (Jantoven), dabigatran (Pradaxa), rivaroxaban (Xarelto), apixaban (Eliquis) and heparin; and anti-platelet agents, such as clopidogrel (Plavix), prasugrel (Effient) and ticagrelor (Brilinta). Some antibiotics and antidepressants also might be associated with clotting problems. As a result, bleeding from damage to small blood vessels near the skin's surface might take longer than usual to stop. This allows enough blood to leak out under the skin to cause a bruise.
Topical and systemic corticosteroids can be used to treat various conditions, including allergies, asthma and eczema. Corticosteroids thin the skin, making it easier to bruise. Certain dietary supplements, such as ginkgo biloba, also can increase bruising risk due to a blood-thinning effect.
If you experience increased bruising, don't stop taking your medications. Talk to your health care provider about your concerns. Also, tell your provider about any supplements you're taking — especially if you're taking them while on a blood-thinning drug. Your provider might tell you to avoid certain nonprescription medications or supplements.