Antibiotics often are the first treatment for an active urinary tract infection. Your health and the type of bacteria in your urine guide which medicine is used and how long you need to take it.
Simple infections
Antibiotics used to treat simple UTIs include:
- Trimethoprim and sulfamethoxazole (Bactrim, Bactrim DS).
- Fosfomycin.
- Nitrofurantoin (Macrodantin, Macrobid, Furadantin).
- Cephalexin.
- Ceftriaxone.
Fluoroquinolones aren't used for most simple UTIs. This group of antibiotics includes ciprofloxacin (Cipro), levofloxacin and others. Their risks tend to outweigh the benefits for simple UTIs. But for complicated UTIs or kidney infections, a a fluoroquinolone medicine might be used if there are no other treatment options.
Often, UTI symptoms begin to clear up within a few days of starting treatment. But it may take some time for inflammation to go down and symptoms to get better. Depending on the infection and the specific medicine, you may need to keep taking antibiotics for a week or more. Take all the medicine as instructed.
For a simple UTI that happens when you're otherwise healthy, a healthcare professional may suggest a shorter course of treatment. That may mean taking an antibiotic for 1 to 3 days. Whether a short course of treatment is enough to treat your infection depends on your symptoms, the type of antibiotic and your medical history.
Your healthcare professional also may give you a medicine to lessen burning when you urinate. But pain tends to go away soon after starting an antibiotic.
Preventing repeat infections
After being treated for a urinary tract infection, it's important to think about ways to prevent an infection from happening again. These steps may help lower your risk of future UTIs:
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Drink plenty of fluids, especially water. Drinking water helps dilute the urine. That leads you to urinate more often. Urinating flushes bacteria away before an infection can start. Aim for 1.5 liters, or around 50 ounces, or more of fluids each day, unless your healthcare team tells you to take in a different amount based on other medical conditions.
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Try topical vaginal estrogen therapy. For women who are in perimenopause or menopause, using a product in the vagina that contains estrogen can help reduce the risk of a repeat UTI. Vaginal estrogen therapy is only appropriate if there are no medical reasons why you shouldn't use estrogen therapy.
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Manage constipation. Eat more fruits, vegetables, beans, whole-grain bread and other fiber-rich foods. Regular physical activity also helps improve the movement of stool through the colon.
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Try cranberry juice. Researchers keep studying cranberry juice and other cranberry products to learn whether they might help prevent UTIs. For now, results are unclear. There's little harm in drinking cranberry juice if you feel it helps you prevent UTIs, but watch the calories and sugar in some products. For most people, drinking cranberry juice is safe. Some people report an upset stomach or diarrhea. Don't drink cranberry juice if you're taking blood-thinning medicine, such as warfarin (Jantovin).
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Avoid feminine products that might irritate the skin. Deodorant sprays, douches and powders in the genital area can irritate the urethra.
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Change your birth control method. Diaphragms, condoms that are not lubricated and condoms treated with spermicide can add to bacterial growth.
Your healthcare professional may talk with you about other strategies to keep UTIs from coming back. These strategies may include taking certain supplements or medicines that aren't antibiotics.
Frequent infections despite preventive efforts
Sometimes UTIs keep coming back even with careful use of preventive strategies that don't involve antibiotics. When this happens, your healthcare professional may suggest other ways of using antibiotics, such as:
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Diagnosing and treating yourself when symptoms occur. This is called self-start therapy. You'll be asked to stay in touch with your healthcare professional during self-start therapy.
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Taking a single dose of an antibiotic after sex if your UTIs seem to happen after sexual activity.
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Using low-dose antibiotics for an extended period. You might take them for six months or longer.
Antibiotics can have unwanted side effects, such as a skin rash, upset stomach or loose stools. Overuse of antibiotics also can lead to antibiotic resistance. Antibiotic resistance happens when bacteria become stronger than the drugs designed to kill them. That's why it's important to try to prevent UTIs from coming back with strategies that don't use antibiotics.
Severe infections
For severe UTIs, you may need IV antibiotics given in a hospital.