Once your healthcare professional learns the cause of the transient ischemic attack, the goal of treatment is to correct the issue and prevent a stroke. You may need medicines to prevent blood clots. Or you might need surgery.
Medicines
Several medicines may lower the risk of stroke after a
TIA. Your healthcare professional recommends a medicine based on what caused the
TIA, where it was located, its type and how bad the blockage was. Your healthcare professional may prescribe:
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Anti-platelet drugs. These medicines make a circulating blood cell called platelets less likely to stick together. Sticky platelets begin to form clots when blood vessels are injured. Clotting proteins in blood plasma also are involved in the process.
Aspirin is the most commonly used anti-platelet medicine. Aspirin is also the least expensive treatment with the fewest potential side effects. An alternative to aspirin is the anti-platelet drug clopidogrel (Plavix).
Aspirin and clopidogrel may be prescribed together for about a month after the
TIA. Research shows that taking these two medicines together in certain situations reduces the risk of a future stroke more than taking aspirin alone.
Sometimes both medicines are taken together for a longer period. This may be recommended when the cause of the
TIA is a narrowing of a blood vessel in the head.
When there's a serious block of a major artery, the medicine cilostazol may be prescribed with aspirin or clopidogrel.
Alternatively, your healthcare professional may prescribe ticagrelor (Brilinta) and aspirin for 30 days to decrease your risk of recurrent stroke.
Your healthcare professional also may consider prescribing a combination of low-dose aspirin and the anti-platelet drug dipyridamole to reduce blood clotting. The way dipyridamole works is slightly different from aspirin.
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Anticoagulants.
These medicines include heparin and warfarin (Jantoven). They lower the risk of blood clots by affecting clotting-system proteins instead of platelet function. Heparin is used for a short time and is rarely used in the management of
TIAs.
These medicines require careful monitoring. If you have atrial fibrillation, your healthcare professional may prescribe a direct oral anticoagulant such as apixaban (Eliquis), rivaroxaban (Xarelto), edoxaban (Savaysa) or dabigatran (Pradaxa), which may be safer than warfarin due to lower bleeding risk.
Surgery
If the carotid artery in the neck is very narrowed, your healthcare professional may suggest a surgery called carotid endarterectomy (end-ahr-tur-EK-tuh-me). This preventive surgery clears carotid arteries of fatty deposits before another
TIA or stroke can occur. An incision is made to open the artery, the plaques are removed, and the artery is closed.
Angioplasty
Some people need a procedure called carotid angioplasty and stent placement. This procedure involves using a balloon-like device to open a clogged artery. Then a small wire tube called a stent is placed into the artery to keep it open.