For a low-grade fever, your care provider may not recommend taking medications to lower your body temperature. These minor fevers may be helpful in reducing the number of microbes causing your illness. Fevers above 102 F (38.9 C) tend to cause discomfort and often require treatment.
Over-the-counter medications
In the case of a high fever or a fever that causes discomfort, your care provider may recommend nonprescription medication, such as acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin IB, others).
Use these medications according to the label instructions or as recommended by your health care provider. Be careful not to take too much. High doses or long-term use of acetaminophen or ibuprofen may cause liver or kidney damage, and acute overdoses can be fatal. Don't give aspirin to children, because it may trigger a rare, but potentially fatal, disorder known as Reye's syndrome.
These medications will usually lower your temperature, but you may still have a mild fever. It may take 1 to 2 hours for the medication to work. Call your care provider if your fever doesn't improve, even after taking medication.
Prescription medications
Your health care provider may prescribe other medications based on the cause of your illness. Treating the underlying cause may lessen signs and symptoms, including fever.
Treatment of infants
Infants, especially those younger than two months old, might need to be admitted to the hospital for testing and treatment. In babies this young, a fever could indicate a serious infection that requires intravenous (IV) medications and round-the-clock monitoring.