Initial treatment depends on the seriousness of the child's asthma. The goal of asthma treatment is to keep symptoms under control, meaning that a child has:
- Minimal or no symptoms.
- Few or no asthma flare-ups.
- No limitations on physical activities or exercise.
- Minimal use of quick-relief inhalers, such as albuterol (ProAir HFA, Ventolin HFA, others). These also are called rescue inhalers.
- Few or no side effects from medicines.
However, if an infant or toddler has frequent or severe wheezing episodes, a health professional might prescribe a medicine to see if it improves symptoms.
Long-term control medicines
Preventive, long-term control medicines reduce the inflammation in a child's airways that leads to symptoms. In most cases, these medicines need to be taken daily.
Types of long-term control medicines include:
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Inhaled corticosteroids. These medicines include fluticasone (Flovent Diskus), budesonide (Pulmicort Flexhaler), mometasone (Asmanex HFA), ciclesonide (Alvesco), beclomethasone (Qvar Redihaler) and others. A child might need to use these medicines for several days to weeks before getting the full benefit.
Long-term use of these medicines has been associated with slightly slowed growth in children, but the effect is minor. In most cases, the benefits of good asthma control outweigh the risks of possible side effects.
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Leukotriene modifiers. These oral medicines include montelukast (Singulair) and zafirlukast (Accolate). They help prevent asthma symptoms for up to 24 hours.
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Combination inhalers. These medicines contain an inhaled corticosteroid plus a long-acting beta agonist (LABA). They include fluticasone and salmeterol (Advair Diskus), budesonide and formoterol (Symbicort), fluticasone and vilanterol (Breo Ellipta), and mometasone and formoterol (Dulera).
In some situations, long-acting beta agonists have been linked to severe asthma attacks. For this reason, LABA medicines should always be given to a child with an inhaler that also contains a corticosteroid. These combination inhalers should be used only for asthma that's not well controlled by other medicines.
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Biologics. Mepolizumab (Nucala), dupilumab (Dupixent) and benralizumab (Fasenra) might be appropriate for children over the age of 6 who have severe eosinophilic asthma. Omalizumab (Xolair) can be considered for children age 6 and older who have moderate to severe allergic asthma. Tezepelumab (Tezspire) is a biologic approved for children age 12 and older who have severe asthma.
Quick-relief medicines
Quick-relief medicines quickly open swollen airways. Also called rescue medicines, quick-relief medicines are used as needed for rapid, short-term symptom relief during an asthma attack — or before exercise if a healthcare professional recommends it.
Types of quick-relief medicines include:
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Short-acting beta agonists (SABAs). These inhaled bronchodilator medicines can quickly ease symptoms during an asthma attack. They include albuterol and levalbuterol (Xopenex HFA). These medicines act within minutes, and effects last several hours. Sometimes SABAs may be combined with a corticosteroid.
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Oral and intravenous corticosteroids. These medicines relieve airway inflammation caused by severe asthma. Examples include prednisone and methylprednisolone. They can cause serious side effects when used long term, so they're only used to treat severe asthma symptoms on a short-term basis.
Treatment for allergy-induced asthma
If a child's asthma is triggered or worsened by allergies, the child might benefit from allergy treatment, including:
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Omalizumab. This medicine is for people who have allergies and severe asthma. It reduces the immune system's reaction to allergy-causing substances, such as pollen, dust mites and pet dander. Omalizumab is delivered by injection every four weeks.
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Allergy medicines. These include oral and nasal spray antihistamines and decongestants.
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Immunotherapy. Over time, immunotherapy may gradually reduce a child's immune system reaction to specific allergens. This type of treatment is available as a shot or as a pill dissolved under the tongue.
Don't rely only on quick-relief medicines
Long-term asthma control medicines such as inhaled corticosteroids are the cornerstone of asthma treatment. These medicines keep asthma under control and make it less likely that a child will have an asthma attack.
If a child does have an asthma flare-up, a quick-relief inhaler, also called a rescue inhaler, can ease symptoms right away. But if long-term control medicines are working properly, a child shouldn't need to use a quick-relief inhaler very often.
Keep a record of how many puffs your child uses each week. If your child often needs to use a quick-relief inhaler, see a healthcare professional. You'll probably need to adjust your child's long-term control medicine.
Inhaled medicine devices
Inhaled short- and long-term control medicines are used by inhaling a measured dose of medicine.
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Older children and teens might use a small, hand-held device called a pressurized metered dose inhaler or an inhaler that releases a fine powder.
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Infants and toddlers need to use a face mask attached to a metered dose inhaler or a nebulizer to get the correct amount of medicine.
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Babies need to use a device that turns liquid medicine into fine droplets, called a nebulizer. The baby wears a face mask and breathes regularly while the nebulizer delivers the correct dose of medicine.
Asthma action plan
Work with your child's healthcare professional to create a written asthma action plan. This can be an important part of treatment, especially if your child has severe asthma. An asthma action plan can help you and your child:
- Recognize when you need to adjust long-term control medicines.
- Determine how well treatment is working.
- Identify the signs of an asthma attack and know what to do when one happens.
- Know when to call a healthcare professional or seek emergency help.
Children who have enough coordination and understanding might use a hand-held device called a peak flow meter. A peak flow meter measures how well they can breathe. A written asthma action plan can help you and your child remember what to do when peak flow measurements reach a certain level.
The action plan might use peak flow measurements and symptoms to categorize your child's asthma into zones, such as a green zone, a yellow zone and a red zone. These zones correspond to well-controlled symptoms, partly controlled symptoms and poorly controlled symptoms. This makes tracking your child's asthma easier.
Your child's symptoms and triggers are likely to change over time. Observe symptoms and work with your child's healthcare professional to adjust medicines as needed.
If your child's symptoms are completely controlled for a time, your child's healthcare team might recommend lowering doses or stopping asthma medicines. This is known as step-down treatment. If your child's asthma isn't as well controlled, the health professional might want to increase, change or add medicines. This is known as step-up treatment.