Amerikan Hastanesi Mayoclinic
  • OUR HOSPITALS
    Select the hospital you want to process.
    • Bodrum Amerikan Hastanesi
    • MedAmerikan Tıp Merkezi
  • OUR SERVICES
  • OUR DOCTORS
  • CONTACT US
  • CORPORATE
  • MAYO CLINIC HEALTH LIBRARY
InternationalPatients
EN
  • American Hospital
  • Member Of Mayo Clinic Care Network
  • Mayo Clinic Health Information Library
  • Faqs
  • Antidepressants: Which Cause The Fewest Sexual Side Effects?
OUR HOSPITALS
  • Bodrum Amerikan Hastanesi
  • Amerikan Tıp Merkezi
Amerikan Hastanesi
  • OUR SERVICES
  • OUR DOCTORS
  • SERVICE LINE
  • NURSING CARE
  • KOÇ HEALTHCARE
  • ONLINE SERVICES
  • PATIENT EXPERIENCE OFFICE
  • PATIENT RIGHTS
  • INTERNATIONAL PATIENTS
  • MEMBER OF MAYO CLINIC CARE NETWORK
  • GUEST GUIDE
  • PERFORMANCE INDICATORS
  • CORPORATE AGREEMENTS
  • CORPORATE AGREEMENTS
  • HUMAN RESOURCES
  • CORPORATE
  • OUR VALUES
  • CONTACT US
  • VIRTUAL TOUR
How Can We Help?
Search
Our Hospitals Corporate Our Services Our Doctors
Choose a Language
  • English
    English
  1. HOMEPAGE
  2. MEMBER OF MAYO CLINIC CARE NETWORK
  3. FAQS
  4. ANTIDEPRESSANTS: WHICH CAUSE THE FEWEST SEXUAL SIDE EFFECTS?
Antidepressants: Which cause the fewest sexual side effects?
Last Updated on November 15, 2023
Answer Section

Sexual side effects are common with antidepressants in both men and women, so your concern is understandable. Effects on sexual function can include:

  • A change in your desire for sex
  • Erectile problems
  • Orgasm problems
  • Problems with arousal, comfort and satisfaction

The severity of sexual side effects depends on the individual and the specific type and dose of antidepressant. For some people, sexual side effects are minor or may ease up as their bodies adjust to the medication. For others, sexual side effects continue to be a problem.

Antidepressants with the lowest rate of sexual side effects include:

  • Bupropion (Wellbutrin XL, Wellbutrin SR)
  • Mirtazapine (Remeron)
  • Vilazodone (Viibryd)
  • Vortioxetine (Trintellix)

Antidepressants most likely to cause sexual side effects include:

  • Selective serotonin reuptake inhibitors (SSRIs), which include citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil, Pexeva) and sertraline (Zoloft).
  • Serotonin and norepinephrine reuptake inhibitors (SNRIs), which include venlafaxine (Effexor XR), desvenlafaxine (Pristiq) and duloxetine (Cymbalta).
  • Tricyclic and tetracyclic antidepressants, such as amitriptyline, nortriptyline (Pamelor) and clomipramine (Anafranil).
  • Monoamine oxidase inhibitors (MAOIs), such as isocarboxazid (Marplan), phenelzine (Nardil) and tranylcypromine (Parnate). However, selegiline (Emsam), an MAOI that you stick on your skin as a patch, has a low risk of sexual side effects.

If you're taking an antidepressant that causes sexual side effects, your doctor may recommend one or more of these strategies:

  • Waiting several weeks to see whether sexual side effects get better.
  • Adjusting the dose of your antidepressant to reduce the risk of sexual side effects. But always talk with your doctor before changing your dose.
  • Switching to another antidepressant that may be less likely to cause sexual side effects.
  • Adding a second antidepressant or another type of medication to counter sexual side effects. For example, the addition of the antidepressant bupropion may ease sexual side effects caused by another antidepressant.
  • Adding a medication to improve sexual function, such as sildenafil (Viagra), tadalafil (Cialis) or vardenafil (Levitra, Staxyn). These medications are approved by the Food and Drug Administration only to treat sexual problems in men. Limited research suggests that sildenafil may improve sexual problems caused by antidepressants in some women, but more information is needed on its effectiveness and safety in women.

Stopping medication because of sexual side effects is a common problem, and for most people this means depression returns. Work with your doctor to find an effective antidepressant or combination of medications that will reduce your sexual side effects and keep your depression under control.

If you're pregnant or trying to become pregnant, tell your doctor, as this may affect the type of antidepressant that's appropriate.

Be patient. Everyone reacts differently to antidepressants, so it may take some trial and error to identify what works best for you.

Test diagnosis tab content
Test doctor tab content
©1998-2024 Mayo Foundation for Medical Education and Research.All rights reserved
Terms of Use
CODE LOTUS
OUR SERVICES
FINESSE AND PERFECTION CENTER
OUR DOCTORS
CONTACT US
CORPORATE
  • The Vehbi Koç Foundation (VKV) and Board of Directors
  • Our values
  • Message of CEO
  • Organization Chart and Management
  • HUMAN RESOURCES

  • History
NEWS
GUEST GUIDE
  • Corporate Agreements
  • Patient Admission Process
  • Accompanying Policy
  • Plan Your Visit
  • Frequently Asked Questions
ONLINE SERVICES
  • Web Baby
  • Lab Results
CONTACT FORM

Our team of experts will answer your questions as soon as possible.

For more detailed information about your personal data, please read the Patient Privacy Notice

  • amerikan hospital logo
  • amerikan tıp merkezi logo
  • koc hospital logo

2025, Copyright American Hospital

Virtual Tour
Protection of Personal Data
Information Society Services
Contact : +90 212 444 3 777
Manage Cookie Preferences
  • certifica1
  • certifica2
Design & Developed by POMPAA