Treatment differs, depending on whether you have primary or secondary cough headaches.
Primary cough headache
If you have a history of primary cough headaches, your doctor may recommend that you take daily medication to help prevent or reduce the pain.
These preventive medications may include:
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Indomethacin (Indocin), an anti-inflammatory drug
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Propranolol (Inderal LA), a medication that relaxes blood vessels and reduces blood pressure
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Acetazolamide, a diuretic that reduces the amount of spinal fluid, which can reduce the pressure inside the skull
Other medications used to treat primary cough headache include methysergide, naproxen sodium (Aleve), methylergonovine, intravenous dihydroergotamine (D.H.E. 45) and phenelzine (Nardil).
Secondary cough headache
If you have secondary cough headaches, surgery is often needed to fix the underlying problem. Preventive medications usually don't help people who have secondary cough headaches. However, responding to medication doesn't necessarily mean that you have a primary cough headache.